Inhibin A and B, Tumor Marker, Serum
Use
This test is used for aiding in the diagnosis of granulosa cell tumors and mucinous epithelial ovarian tumors as well as monitoring patients with such tumors known to secrete inhibin A or overexpress inhibin B. Inhibins, which are heterodimeric protein hormones, play a role in the regulation of follicle-stimulating hormone (FSH) and have paracrine actions in the gonads. Elevated levels of inhibin A and B are detected in some patients with granulosa cell tumors and certain types of epithelial ovarian tumors.
Special Instructions
For accurate results, it is important to follow collection instructions: centrifuge and aliquot serum into a plastic vial. Minimum volume required for testing is 0.9 mL. It is critical to use the same testing method for serial test monitoring. Caution should be used for premenopausal women due to inhibin value fluctuations during the menstrual cycle.
Limitations
Inhibin levels vary with the menstrual cycle in premenopausal women, making interpretation challenging. Results should be considered along with clinical evaluation and other diagnostic procedures, as tumor markers are not specific for malignancy and may vary by testing methodology. The test hasn't been cleared or approved by the US FDA.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 87426-3
- 23883-2
- 56940-0
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.1 mL
Minimum Volume
0.9 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 90 days |