Iodine, Serum
Use
This test is useful for determining iodine overload using serum specimens and for monitoring iodine levels in individuals taking iodine-containing drugs. Iodine is an essential element required for thyroid hormone production, and its measurement serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs, such as amiodarone.
Special Instructions
Disinfectants containing iodine, such as Betadine, should not be used during specimen collection. High concentrations of gadolinium and iodine can interfere with the test, and if either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Limitations
There are no known analytical interferences with this procedure. However, the administration of iodine-containing contrast media will yield elevated results.
New York Approved
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
LOINC Codes
- 2494-3
- 2494-3
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Plain, royal blue-top Vacutainer plastic trace element blood collection tube
Collection Instructions
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper, carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood.
Patient Preparation
Disinfectants containing iodine should not be used. Avoid specimen collection for 96 hours after administering iodine or gadolinium-containing contrast media.
Storage Instructions
Refrigerated (preferred): 28 days; Ambient: 28 days; Frozen: 28 days
Causes for Rejection
Gross hemolysis, OK; Gross lipemia, OK; Gross icterus, OK
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |