Iodine, Serum
Use
This test is useful for determining iodine overload using serum specimens and for monitoring iodine levels in individuals taking iodine-containing drugs. Iodine is an essential element required for thyroid hormone production, and its measurement serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs, such as amiodarone.
Special Instructions
Not provided.
Limitations
There are no known analytical interferences with this procedure. However, the administration of iodine-containing contrast media will yield elevated results.
New York Approved
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
LOINC Codes
- 2494-3 - Iodine SerPl-mCnc
- 2494-3 - Iodine SerPl-mCnc
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Plain, royal blue-top Vacutainer plastic trace element blood collection tube
Collection Instructions
Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Remove the stopper, carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood.
Patient Preparation
Disinfectants containing iodine should not be used. Avoid specimen collection for 96 hours after administering iodine or gadolinium-containing contrast media.
Storage Instructions
Refrigerated (preferred): 28 days; Ambient: 28 days; Frozen: 28 days
Causes for Rejection
Gross hemolysis, OK; Gross lipemia, OK; Gross icterus, OK
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |