Isoniazid (INH)
Use
Isoniazid is an antibiotic used for the prevention and treatment of tuberculosis. This test measures the level of isoniazid in the serum to ensure therapeutic levels are achieved while avoiding toxicity. Monitoring of serum levels can be particularly important in patients who have hepatic dysfunction, are receiving other potentially hepatotoxic drugs, or are in a relapse phase of treatment.
Special Instructions
Not provided.
Limitations
The performance characteristics of the test were determined by LabCorp. It has not been cleared or approved by the FDA, indicating it should be used following specific clinical guidelines. Serum gel tubes are not acceptable for collection as they may affect the test results. Specimens showing hemolysis, lipemia, or icterus are not acceptable for testing.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Isoniazid
Analyte
LOINC Codes
- 3697-0 - Isoniazid SerPl-mCnc
- 3697-0 - Isoniazid SerPl-mCnc
Result Turnaround Time
5-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
Red-top tube
Collection Instructions
Draw blood in a plain red-top tube (serum gel tube is not acceptable). Spin down and send 2 mL of serum refrigerated in a plastic vial.
Causes for Rejection
Hemolysis, lipemia, icterus, or other unacceptable conditions.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 180 days |