Ispaghula, IgE, Serum
Use
The Ispaghula, IgE test is used to establish a diagnosis of allergy to ispaghula and to define the allergen responsible for eliciting signs and symptoms. It helps identify allergens responsible for allergic responses or anaphylactic episodes, confirm sensitization before immunotherapy, and investigate specific allergic reactions to insect venom, drugs, or chemicals. This test can assist in determining the immune response by detecting IgE antibodies that may be associated with allergic diseases.
Special Instructions
If ordering manually, complete, print, and send an Allergen Test Request form (T236) with the specimen. The test can be ordered from New York State clients as it is NY State approved.
Limitations
IgE antibody testing is not useful in patients previously treated with immunotherapy to determine residual clinical sensitivity or in cases where medical management is unaffected by allergen specificity. False positives can occur due to nonspecific binding or in patients with significantly elevated IgE levels (>2500 kU/L). Clinical context is crucial for interpreting results as some individuals with insignificant sensitivity may have measurable IgE levels.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6150-7
- 6150-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; for more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated (preferred) for 14 days or frozen for 90 days.
Causes for Rejection
None noted for gross hemolysis or gross lipemia.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |