Japanese Cedar, IgE, Serum

Casandra

Casandra Test Code MC80697Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID JCEDRCPT Code 86003

Japanese Cedar, IgE, Serum

Clinical Use

Use

This test is useful for establishing a diagnosis of an allergy to Japanese cedar by detecting specific IgE antibodies in the serum. It helps define the allergen responsible for eliciting signs and symptoms and confirms sensitization prior to beginning immunotherapy. It may also investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine residual clinical sensitivity or in cases where medical management does not rely on allergen specificity identification.

Special Instructions

Reference values apply to all ages. Concentrations of 0.70 kU/L or more (class 2 and above) will flag as abnormally high. If not ordering electronically, complete and send an Allergen Test Request form (T236) with the specimen. The test uses the ImmunoCAP System for IgE detection, indicating a relation of the immune response to allergens that may be associated with allergic disease.

Limitations

Some individuals with clinically insignificant sensitivity to allergens may have measurable IgE antibody levels, so results must be interpreted in context. False-positive results may occur in patients with markedly elevated serum IgE due to nonspecific binding. The test is not useful for monitoring previously treated patients with immunotherapy or cases where management does not depend on allergen specificity.

Test Details

New York Approved