Ki-67(MIB-1), Gastrointestinal/Pancreatic Neuroendocrine Tumors, Quantitative Immunohistochemistry, Automated
Use
This test is useful for determining the proliferation of tumor cells in paraffin-embedded tissue blocks from patients diagnosed with neuroendocrine tumors of the pancreas or gastrointestinal tract, including metastases. By measuring the amount of tumor cells expressing the Ki-67 antigen, an estimate of DNA synthesis can be determined. Studies suggest that Ki-67(MIB-1) analysis in paraffin-embedded tissue specimens provides useful prognostic information in various tumor types.
Special Instructions
Not provided.
Limitations
The paraffin block analyzed must be representative of the patient's tumor. Test results should be interpreted in the context of clinical findings and other laboratory data. Cases that cannot be scanned for automated analysis will be changed to manual process for analysis.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Ki-67
Protein
LOINC Codes
- 29593-1 - Ki-67 nuclear Ag NFr Tiss ImStn
- 29593-1 - Ki-67 nuclear Ag NFr Tiss ImStn
- 19139-5 - Pathologist name
- 81178-6 - Block description and site Spec
- 62364-5 - Test performance info Spec
- 80398-1 - Unique ID Current sample
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Pathology Packaging Kit
Collection Instructions
Submit formalin-fixed, paraffin-embedded tissue block.
Causes for Rejection
No specimen should be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |