Lactotransferrin Immunostain, Technical Component Only
Use
This test is used for identifying the presence of lactotransferrin in amyloid deposits and serves as an adjunct to amyloid-subtyping analysis by mass spectrometry. Lactotransferrin is known to be expressed in various tissues and plays a role in iron metabolism and defense against bacteria. It is also associated with amyloidosis in certain tissues.
Special Instructions
Not provided.
Limitations
The test does not include a pathologist's interpretation. Age of paraffin sections and environmental factors affecting glass slides can impact immunoreactivity and staining results. Best practices include minimizing storage time of slides after unpacking, limiting exposure to humidity and heat, and ensuring proper glass slide chemistry.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Lactotransferrin
Protein
LOINC Codes
- Order only
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Use formalin-fixed, paraffin-embedded tissue block or 2 unstained, positively charged glass slides per test ordered.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin-fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |