Langerin Immunostain, Technical Component Only
Use
The Langerin Immunostain test is useful for the visualization of normal and neoplastic Langerhans cells. Langerhans cells are specialized antigen-presenting cells located in the skin, and Langerin is expressed in these cells both under normal conditions and in pathological states. This test aids in the identification of these cells through immunohistochemical staining, providing crucial insights in clinical diagnostics relating to skin disorders and other conditions where Langerhans cells are implicated.
Special Instructions
Not provided.
Limitations
The charge of glass slides can be affected by environmental factors, potentially altering stain effectiveness. It is important to minimize the time slides are stored once unpackaged and to limit their exposure to high humidity, heat, and certain plastics that may interfere. Additionally, the age of a paraffin section can influence immunoreactivity, with sections cut within six weeks being preferable for maintaining optimal staining quality.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Langerin
Protein
LOINC Codes
- Order only;no result
- Bill only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Storage Instructions
Ambient (preferred) or refrigerated transport
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides