Macadamia Nut, IgE, Serum
Use
Testing establishes the diagnosis of an allergy to macadamia nut and defines the allergen responsible for eliciting signs and symptoms. It is useful in identifying allergens responsible for allergic response and/or anaphylactic episode, confirming sensitization prior to beginning immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
This test is performed Monday through Friday, and orders can be placed via an electronic system or through the Allergen Test Request form (T236) if not ordering electronically.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity. Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies. False-positive results may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 11183-1
- 11183-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; More than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Container
Preferred: Serum gel; Acceptable: Red top; Submission Container: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated (preferred): 14 days; Frozen: 90 days
Causes for Rejection
None specified
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
