Measles, Mumps, Rubella, and Varicella (MMRV) Immune Status Profile, Serum
Use
This test is used for determining the immune status of individuals regarding measles, mumps, rubella, and varicella-zoster viruses (VZV). It helps document previous infections with these viruses in individuals who lack a previous immunization record. The presence of IgG-class antibodies implies immunity due to previous exposure or vaccination. Detecting nonimmunity is particularly important for individuals at risk, such as immunocompromised patients, pregnant women, and adults possibly experiencing waning immunity, to prevent outbreaks and severe complications related to these infections.
Special Instructions
Not provided.
Limitations
Results may be affected by patients who recently received blood products or were vaccinated, resulting in false negatives or false positives. Specimens collected shortly after infection or post-vaccination might not display IgG antibodies. Hemolysis, lipemia, icterus, or improper refrigeration may lead to rejection.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Multiplex Flow Immunoassay)
Biomarkers
LOINC Codes
- 104688-7 - MMR & VZV pnl SerPl
- 15410-4 - VZV IgG Ser Ql IA
- 5403-1 - VZV IgG Ser IA-aCnc
- 40667-8 - RUBV IgG SerPl Ql IA
- 5334-8 - RUBV IgG SerPl IA-aCnc
- 25418-5 - MuV IgG Ser IA-aCnc
- 6476-6 - MuV IgG Ser Ql IA
- 35275-7 - MeV IgG Ser Ql IA
- 5244-9 - MeV IgG Ser IA-aCnc
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, and heat-inactivated specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |