Measles, Mumps, Rubella, and Varicella (MMRV) Immune Status Profile, Serum
Use
This test is used for determining the immune status of individuals regarding measles, mumps, rubella, and varicella-zoster viruses (VZV). It helps document previous infections with these viruses in individuals who lack a previous immunization record. The presence of IgG-class antibodies implies immunity due to previous exposure or vaccination. Detecting nonimmunity is particularly important for individuals at risk, such as immunocompromised patients, pregnant women, and adults possibly experiencing waning immunity, to prevent outbreaks and severe complications related to these infections.
Special Instructions
For accurate results, ensure specimens are handled per provided instructions and submitted in the recommended collection containers. Forms like the Kidney Transplant Test Request or Infectious Disease Serology Test Request (T916) might be needed when not ordering electronically.
Limitations
Results may be affected by patients who recently received blood products or were vaccinated, resulting in false negatives or false positives. Specimens collected shortly after infection or post-vaccination might not display IgG antibodies. Hemolysis, lipemia, icterus, or improper refrigeration may lead to rejection.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Multiplex Flow Immunoassay)
Biomarkers
LOINC Codes
- 104688-7
- 15410-4
- 5403-1
- 40667-8
- 5334-8
- 25418-5
- 6476-6
- 35275-7
- 5244-9
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, and heat-inactivated specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |