Megrim, IgE, Serum
Use
This test is useful for establishing the diagnosis of an allergy to megrim and defining the allergen responsible for eliciting signs and symptoms. It can identify allergens responsible for allergic responses and/or anaphylactic episodes, confirm sensitization prior to beginning immunotherapy, and investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen. Gross hemolysis and lipemia are acceptable.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients where the management does not rely on allergen specificity. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding.
New York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay)
Biomarkers
LOINC Codes
- 10939-7
- 10939-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen; more than 0.05 mL for each additional allergen + 0.25 mL dead space
Container
Collection Container/Tube: Preferred: Serum gel; Acceptable: Red top. Submission Container/Tube: Plastic vial.
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Specimen Stability Information: Refrigerated (preferred): 14 days; Frozen: 90 days.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |