Microsporidia species, Molecular Detection, PCR, Varies
Use
This test is useful for detecting Enterocytozoon bieneusi and Encephalitozoon species in fecal and urine specimens, supporting the clinical diagnosis of microsporidiosis. The test is particularly relevant for immunocompromised patients who present with persistent, watery diarrhea. Microsporidiosis is caused by highly specialized fungi known as microsporidia, and this assay targets the most common species responsible for intestinal and renal infections. The detection of these species can assist in diagnosing microsporidiosis in contexts where other diagnostic methods may be insufficient.
Special Instructions
Not provided.
Limitations
This assay is designed to detect symptomatic infection with Enterocytozoon bieneusi and Encephalitozoon species but may indicate asymptomatic carriage. It cannot detect microsporidiosis caused by less common species and should only be used for patients with clinical symptoms consistent with microsporidiosis. A negative result does not definitively rule out infection. Other diagnostic tests may be necessary for a comprehensive evaluation.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
Encephalitozoon species
MicroorganismEnterocytozoon bieneusi
Microorganism
LOINC Codes
- 94332-4 - Microsporidia 18S rRNA Pnl NAA+non-prb
- 31208-2 - Specimen source
- 94333-2 - Encephalitozoon 18S rRNA Spec Ql NAA+prb
- 94334-0 - E bieneusi 18S rRNA Spec Ql NAA+non-prb
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
5 g
Minimum Volume
1 g
Container
Stool container, Small (Random) or ECOFIX preservative
Causes for Rejection
Feces in preservatives other than ECOFIX
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 7 days |