Milk, IgE, Serum
Use
This test is used to establish a diagnosis of an allergy to milk by measuring specific IgE antibodies in serum. The test helps define the allergen responsible for eliciting allergic reactions and can confirm sensitization prior to starting immunotherapy. It is valuable in investigating the specificity of allergic reactions to various allergens, including insect venoms, drugs, and chemicals. The test results aid in identifying allergens that are responsible for allergic responses and potential anaphylactic episodes.
Special Instructions
An Allergen Test Request form (T236) should be completed and sent along with the specimen if not ordering electronically. For a list of available allergens for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies PDF. The specimen should be centrifuged and the serum aliquoted into a plastic vial.
Limitations
This test is not useful in patients who have already undergone immunotherapy, as it does not determine residual clinical sensitivity. False-positive results may occur in patients with very high serum IgE levels (>2500 kU/L) due to nonspecific binding. Results should be interpreted in the context of the clinical situation as some individuals with insignificant allergen sensitivity may have detectable IgE antibodies.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6174-7
- 6174-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |