MiTF Immunostain, Technical Component Only
Use
This test is useful for the identification of melanomas. It involves the detection of microphthalmia-associated transcription factor, which is produced by melanocytes and osteoclasts, and can assist in the classification of melanoma.
Special Instructions
This test includes only the technical performance of the stain; it does not include pathologist interpretation. If interpretation is required, PATHC / Pathology Consultation must be ordered separately. Ordering this test with PATHC will result in the technical component stains being canceled.
Limitations
Age of a cut paraffin section can affect immunoreactivity. Stability of antigens varies widely among different publications and is antigen dependent, making it best practice for paraffin sections to be cut within 6 weeks. Environmental factors can affect the charge of glass slides, potentially impacting staining results. Unsuitable glass slides may result in inconsistent staining due to poor slide surface chemistry.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Storage Instructions
Ambient temperature is preferred for transporting the specimen.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.