Moth, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to moth. It helps in defining the specific allergen responsible for eliciting signs and symptoms such as allergic reactions or anaphylactic episodes. Additionally, it can confirm sensitization before beginning immunotherapy and investigate allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful for patients who have been previously treated with immunotherapy for determining residual clinical sensitivity or in cases where medical management does not depend on identification of allergen specificity.
Special Instructions
If not ordering electronically, complete, print, and send an Allergen Test Request Form (T236) with the specimen. For a listing of allergens available for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies document.
Limitations
Some individuals may have clinically insignificant sensitivity to allergens, yet exhibit measurable levels of IgE antibodies in serum. False-positive results can occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. It's important to interpret test results in the context of the clinical picture.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 7502-8
- 7502-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; More than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |