Mouse Urine Protein, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to mouse urine protein and defining the specific allergen responsible for eliciting signs and symptoms. It is helpful in identifying allergens responsible for allergic response and/or anaphylactic episodes, confirming sensitization prior to immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in cases where medical management does not depend on identifying allergen specificity.
Special Instructions
Collection of serum is required. Use a serum gel collection container if preferred or a red top tube as acceptable alternatives. After collection, serum should be centrifuged and aliquoted into a plastic vial for submission.
Limitations
While in vitro serum testing for IgE antibodies can indicate an immune response associated with allergic disease, false-positive results may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. Therefore, test results must be interpreted in the clinical context, especially in individuals with clinically insignificant sensitivity to allergens who may still exhibit measurable levels of IgE antibodies.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6181-2
- 6181-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL, multiple allergens require adjustment (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |