Mugwort, IgE, Serum
Use
This test aids in establishing a diagnosis of an allergy to mugwort by identifying specific IgE antibodies in serum. It is useful for defining allergens responsible for allergic reactions and confirming sensitization prior to immunotherapy. Testing can also help in investigating allergic reactions to insect venom, drugs, or chemicals. Such testing is particularly relevant to patients demonstrating symptoms that may be allergen-induced, including symptoms of anaphylaxis.
Special Instructions
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual sensitivity remains, or in cases where medical management doesn't depend on allergen identification. Proper specimen collection and handling are crucial to avoid diagnostic confusion.
Limitations
The presence of measurable IgE antibodies does not always correlate with clinical allergies, as individuals with insignificant sensitivities might still have detectable IgE levels. Additionally, false positive results may occur in patients with very high total IgE levels due to non-specific binding. It is also not suitable for monitoring patients previously treated with immunotherapy.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6183-8
- 6183-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen or (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |