MVista Blastomyces Quantitative Antigen, Fluid
Use
The MVista Blastomyces Quantitative Antigen test is used for the detection and quantification of Blastomyces antigen in cerebrospinal fluid (CSF) or bronchoalveolar lavage fluid. This test helps in the diagnosis of blastomycosis, a fungal infection caused by Blastomyces dermatitidis, potentially aiding in the management and monitoring of the disease. It's particularly useful in cases where direct culture may be negative or delayed, providing a rapid indication of infection.
Special Instructions
The test requires a separate order for each specimen type. Specimens should be collected in sterile, leak-proof screw cap containers and sent refrigerated. Care should be taken as treatment with substances like Sputolysin, sodium hydroxide, and potassium hydroxide can degrade the analyte, affecting test results.
Limitations
Cross-reactivity can occur with other fungi such as Histoplasma spp., Coccidioides spp., and other listed fungi, which may lead to diagnostic confusion. Spinal fluid or bronchoalveolar fluid specimens are necessary, with specific minimum volumes required to obtain accurate results. Inappropriate specimen collection or handling can lead to inaccuracies, and specimens contaminated with certain chemicals can lead to rejection. The test has not been cleared or approved by the FDA, limiting its use to certain regulatory environments.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 31208-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
2 mL
Minimum Volume
0.8 mL
Container
Sterile, leak-proof screw cap container
Collection Instructions
Collect 2 mL of CSF or bronchoalveolar lavage fluid; submit specimen in a sterile, leak-proof screw cap container labeled with specimen type; send refrigerate.
Storage Instructions
Send refrigerated.
Causes for Rejection
Specimen that is too viscous to pipette; specimen in transport media, fixative or Isolator tubes; tissue, biopsy, sputum, bronchial brush, tracheal aspirate, fine needle aspirate, bone marrow aspirate, or stool specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |