Mycoplasma pneumoniae Antibodies, IgG and IgM, Serum
Use
Screening for recent or past exposure to Mycoplasma pneumoniae. The test helps in identifying IgG and IgM antibodies to M pneumoniae in serum, which is used to provide exposure information. It should not be used as a screening procedure for the general population, as detection of IgM or IgG class antibodies provides exposure information rather than confirmation of active infection. The presence of antibodies provides information about prior exposure, and possibly disease.
Special Instructions
Not provided.
Limitations
Serology-based assays for M pneumoniae have several drawbacks. The development of IgM antibodies takes approximately 1 week, and the IgM may vary in adults or be decreased in immunosuppressed individuals. The test results should be interpreted with clinical evaluation and other diagnostic results. Cross-reactivity with organisms like Mycoplasma hominis and Ureaplasma species has not been thoroughly studied, potentially leading to inaccurate diagnoses especially if cross-reactive organisms are present. Test should not be used solely for infection diagnosis without other clinical correlation.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 58733-7 - M pneumo IgG+IgM pnl Ser
- 45224-3 - M pneumo IgG Ser Ql IA
- 5257-1 - M pneumo IgM Ser Ql IA
- 69048-7 - Immunologist review
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, heat inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |