Mycoplasma pneumoniae Antibodies, IgG, Serum
Use
Screening for IgG antibodies to suggest recent or past exposure to Mycoplasma pneumoniae, which is known to cause upper respiratory infections and community-acquired pneumonia. This test helps in confirming past exposure, especially for retrospective testing due to the time required for IgG response elevation. It offers insights into infections that have significant extrapulmonary complications.
Special Instructions
Not provided.
Limitations
The test should not be the sole basis of diagnosis for Mycoplasma pneumoniae infections. Serological testing's limitations include delayed IgM sensitivity, especially in adults, and the inability to confirm acute infections from a single specimen. Antibody presence or absence cannot confirm therapeutic success or failure. Not suitable as a general screening tool and isn't validated for neonates or the immunocompromised. Cross-reactivity with organisms causing lower respiratory illness or related bacteria has not been evaluated.
Methodology
Immunoassay (EIA)
Biomarkers
M. pneumoniae IgG
Protein
LOINC Codes
- 45224-3 - M pneumo IgG Ser Ql IA
- 45224-3 - M pneumo IgG Ser Ql IA
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, and heat inactivated specimen.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |
