Myelodysplastic Syndrome (MDS), Specified FISH, Varies
Use
This test is useful for detecting recurrent common chromosome abnormalities associated with myelodysplastic syndromes (MDS) or other myeloid malignancies using client-specified probe sets. It serves as an adjunct to conventional chromosome studies in patients with MDS, helps evaluate specimens where chromosome studies were unsuccessful, and assists in identifying and tracking known chromosome abnormalities in patients with MDS, as well as monitoring their response to therapy.
Special Instructions
Not provided.
Limitations
This test is not a substitute for conventional chromosome studies, as it may not detect chromosome abnormalities associated with other hematological disorders that could go undetected in a targeted MDS FISH test. It is not FDA approved and is best used as an adjunct to existing clinical and pathologic information. Cases with no FISH signals post-hybridization indicate a lack of FISH results, and if no cells are available for analysis, no charges will be incurred.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 62367-8 - Chrom analy pnl FISH
- 50397-9 - Mol dx interp Bld/T Ql
- 69965-2 - Clinical cytogeneticist review
- 93356-4 - Cells w cytogenetic abnl Bld/T
- 62356-1 - Chrom analy result (ISCN)
- 42349-1
- 78040-3 - FISH probe target gene Lab Device
- 31208-2 - Specimen source
- 85069-3 - Lab test method
- 48767-8 - Annotation comment Imp
- 62364-5 - Test performance info Spec
- 18771-6 - Provider signing name
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
2 to 3 mL
Minimum Volume
1 mL
Container
Yellow top (ACD)
Collection Instructions
It is preferable to send the first aspirate from the bone marrow collection. Invert several times to mix bone marrow. Send bone marrow in original tube. Do not aliquot.
Causes for Rejection
Fresh tissue