Myoglobin Immunostain, Technical Component Only
Use
Myoglobin is a marker for skeletal and cardiac muscle, but not for smooth muscle. It serves as an oxygen transporter pigment. Antibodies to myoglobin can aid in the diagnosis of rhabdomyosarcomas, although the proportion of positive cells may be small and unevenly distributed in tissue sections. Additionally, myoglobin staining is not observed in carcinomas or other sarcomas, making it a specific marker for muscle-related conditions.
Special Instructions
Not provided.
Limitations
Interpretation of this test should be carried out in conjunction with the patient's clinical history and other diagnostic tests by a qualified pathologist. Factors such as the age of paraffin sections and environmental conditions can influence immunoreactivity and slide staining quality. For best results, paraffin sections should be cut within 6 weeks. Proper storage and handling of glass slides are crucial to avoid variations in staining results.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Myoglobin
Protein
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Submit formalin-fixed, paraffin-embedded tissue blocks or 2 unstained, positively charged glass slides per test, each 4-microns thick.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.