Nettle, IgE, Serum
Use
The Nettle, IgE, Serum test is useful for diagnosing allergies related to nettle exposure. It helps in identifying the allergen responsible for allergic reactions, determining the specificity of allergic responses to various allergens including insect venoms, drugs, or chemicals. This test also confirms sensitization prior to immunotherapy initiation. However, it is not useful in assessing residual clinical sensitivity post-immunotherapy or when allergen specificity does not influence patient management.
Special Instructions
When ordering this test, it is recommended to complete the Allergen Test Request form (T236) if not ordering electronically. Ensure to aliquot the serum into a plastic vial after centrifugation. For inquiries regarding the fee schedules, prospective clients should contact their account representative.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine residual clinical sensitivity. Additionally, care must be taken when interpreting results, as some patients with clinically insignificant allergies may present with measurable IgE antibodies. False positives may occur in cases of significantly elevated serum IgE levels due to nonspecific binding.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6186-1
- 6186-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen
Container
Serum gel or red top; submission in plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis or lipemia are acceptable
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |