Ovalbumin, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to ovalbumin, defining the allergen responsible for eliciting signs and symptoms, identifying allergens responsible for allergic response or anaphylactic episodes, confirming sensitization prior to beginning immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It provides an indication of the immune response to allergens that may be associated with allergic disease.
Special Instructions
For a listing of allergens available for testing, see the provided PDF. If not ordering electronically, complete and send an Allergen Test Request Form (T236) with the specimen. Day(s) performed: Monday through Friday.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon identification of allergen specificity. False-positive results may occur in patients with markedly elevated serum IgE due to nonspecific binding.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 7556-4
- 7556-4
Result Turnaround Time
0-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL, For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel, Acceptable: Red top, Submission Container: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Refrigerated (preferred): 14 days, Frozen: 90 days
Causes for Rejection
Gross hemolysis: OK, Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
