Penicillin G, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to penicillin G. It helps define the allergen responsible for eliciting signs and symptoms, and identify allergens responsible for allergic responses and/or anaphylactic episodes. The test is also used to confirm sensitization prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
For a listing of allergens available for testing, see the Allergens - Immunoglobulin E (IgE) Antibodies document. If not ordering electronically, complete and send an Allergen Test Request form (T236) with the specimen. The test must be performed on serum collected in a serum gel or red top tube and requires centrifugation and aliquoting into a plastic vial.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine residual clinical sensitivity or in cases where medical management does not depend on identifying allergen specificity. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE levels (>2500 kU/L) due to nonspecific binding to allergen solid phases. Results should be interpreted in the clinical context, as some individuals with clinically insignificant sensitivity to allergens may show measurable IgE levels.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6851-0
- 6851-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial. Use serum gel as preferred collection container; a red top tube is acceptable.
Causes for Rejection
Only gross hemolysis and lipemia are acceptable
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |