Phospholipase A2 Receptor (PLA2R), Renal Biopsy
Use
Anti‑PLA2R immunofluorescence staining on renal biopsy tissue helps distinguish primary membranous nephropathy from secondary membranous nephropathy; most cases of primary membranous nephropathy exhibit autoantibodies against PLA2R on podocytes, and detection supports accurate diagnosis and disease classification.
Special Instructions
Not provided.
Limitations
This test reports positive or negative for PLA2R autoantibody only; it must be interpreted in clinical context. No significant cautionary statements are provided explicitly. A diagnosis cannot rely solely on this test without clinical and pathology correlation.
Methodology
Immunoassay (IHC)
Biomarkers
PLA2R
Protein
LOINC Codes
- 59465-5 - Path Rev
- 81178-6 - Block description and site Spec
- 22634-0 - Path report.gross Spec
- 80398-1 - Unique ID Current sample
- 62364-5 - Test performance info Spec
- 35265-8 - Path Report.addendum Spec
- 19139-5 - Pathologist name
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Frozen)
Volume
Not provided
Minimum Volume
Not provided
Container
Unstained frozen tissue on slide
Collection Instructions
Submit 2 frozen unstained positively charged glass slides (25×75×1 mm), sections 4 µm thick, centered on slide, submitted on dry ice.
