Pig Epithelium, IgE, Serum
Use
This test is used for establishing a diagnosis of an allergy to pig epithelium by identifying the specific allergen responsible for eliciting signs and symptoms. It helps to confirm sensitization prior to beginning immunotherapy and investigate the specificity of allergic reactions to other allergens. In vitro serum testing for IgE antibodies provides an indication of the immune response to allergens potentially associated with allergic disease. The results offer insight into the allergens responsible for allergic disorders and episodes, aiding in the management and treatment of allergic conditions.
Special Instructions
For each allergen requested in testing, a separate volume of serum is required. Preferred collection is with a serum gel tube, with a red top as an acceptable alternative. Submission must be done using a plastic vial. It's crucial to centrifuge and aliquot the serum into the plastic vial upon preparation. The test is performed Monday through Friday, and electronic ordering includes specific forms. If not ordering electronically, complete and send an Allergen Test Request form with the specimen.
Limitations
Testing for IgE antibodies is not useful in patients who have been previously treated with immunotherapy for an allergy to pig to determine if residual clinical sensitivity exists. False positives may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to non-specific binding to allergen solid phases. Results must be interpreted within the clinical context, as some individuals may have measurable levels of IgE antibodies in serum for allergens that are clinically insignificant.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6262-0
- 6262-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
