Plasma Cell Proliferative Disorder, High Risk with Reflex Probes, Diagnostic FISH Evaluation, Bone Marrow
Use
This test is useful for detecting recurrent high-risk chromosome abnormalities associated with multiple myeloma or other plasma cell proliferative disorders at diagnosis, using a laboratory-designated probe set algorithm. It helps in identifying high-risk prognostic markers associated with multiple myeloma or other plasma cell proliferative disorders. However, this test should not be used to track the progression of the disease.
Special Instructions
Not provided.
Limitations
The test is not FDA approved and serves as an adjunct to existing clinical and pathologic information. It may be canceled if insufficient plasma cells are identified or if there are no FISH signals post-hybridization. It is limited to the detection of specified chromosomal abnormalities related to plasma cell disorders.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
No genes
GeneNo genes
GeneNo genes
Gene
LOINC Codes
- 98014-4 - PC prolif analysis Mar FISH
- 62357-9 - Chrom analy overall interp-Imp
- 69965-2 - Clinical cytogeneticist review
- 93356-4 - Cells w cytogenetic abnl Bld/T
- 62356-1 - Chrom analy result (ISCN)
- 31208-2 - Specimen source
- 39111-0 - Bdy site
- 85069-3 - Lab test method
- 48767-8 - Annotation comment Imp
- 62364-5 - Test performance info Spec
- 18771-6 - Provider signing name
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
4 mL
Minimum Volume
2 mL
Container
Yellow top (ACD) preferred; Green top (sodium heparin) or lavender top (EDTA) acceptable
Collection Instructions
Send the first aspirate from the bone marrow collection. Invert several times to mix. Do not aliquot; send in original tube.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 4 days |