Platelet Surface Glycoprotein, Flow Cytometry, Blood
Use
This test is used for the identification of platelet surface glycoprotein deficiencies which are diagnostic for various hereditary or acquired platelet disorders. It helps in diagnosing conditions such as Glanzmann thrombasthenia and Bernard-Soulier syndrome by measuring the expression levels of specific glycoproteins on the platelet surface using flow cytometry.
Special Instructions
Not provided.
Limitations
Decreased platelet surface receptor expression could result from improper specimen handling, shipping, or storage, affecting the flow cytometry results. Artifacts may occur due to suboptimal sample conditions or benign polymorphisms, and correlation with clinical findings and repeat testing may be necessary.
New York Approved
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 93320-0 - Platelet glycoprotein Pnl Bld FC
- 93319-2 - Plt CD41 Act/Nor Bld FC
- 93318-4 - Plt CD61 Act/Nor Bld FC
- 93317-6 - Plt CD42a Act/Nor Bld FC
- 93316-8 - Plt CD42b Act/Nor Bld FC
- 93315-0 - Plt CD49b Act/Nor Bld FC
- 93314-3 - Plt GPVI Act/Nor Bld FC
- 93313-5 - Platelet GP disorder Bld FC-Imp
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
6 mL
Minimum Volume
1 mL; Pediatric: 200 mcL
Container
ACD solution A or B
Collection Instructions
Send whole blood specimen in original tube. Do not aliquot.
Storage Instructions
Specimen must be kept ambient and sent overnight.
Causes for Rejection
Gross hemolysis, Fully clotted
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |