Platinum, Serum
Use
This test is used to measure the total serum platinum concentrations in patients who have been administered platinum-based chemotherapeutics. Monitoring the platinum levels in the serum is critical for assessing the patient’s response and adjusting the dosage to ensure efficacy while minimizing toxicity. The test helps in understanding the pharmacokinetics and ensuring treatment is within the therapeutic range.
Special Instructions
Not provided.
Limitations
The test has not been cleared or approved by the U.S. Food and Drug Administration, which indicates its usage is based on performance characteristics determined by the performing laboratory, NMS Labs. Interference with testing results can occur if the specimen is collected in polymer gel separation tubes, leading to erroneous readings.
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
Platinum
Analyte
LOINC Codes
- 5714-1 - Platinum SerPl-mCnc
- 5714-1 - Platinum SerPl-mCnc
Result Turnaround Time
8-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Acid washed (MCL Supply T619) or trace metal-free plastic container
Collection Instructions
Draw blood in a plain, royal blue top tube. Spin down the blood and send serum refrigerated in the appropriate container. Serum gel tube is not acceptable.
Causes for Rejection
Polymer gel separation tube (SST or PST)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 60 days |
| Refrigerated | 60 days |
| Frozen | 60 days |
