Psychotropic Pharmacogenomics Gene Panel, Varies
Use
This panel serves to individualize medication selection and dosing for patients undergoing treatment for depression and other psychiatric disorders, based on genetic variation. It identifies genetic factors associated with drug response and risk of adverse effects with psychotropic medications. The analysis may assist in determining the cause of unsuccessful SSRI treatment and evaluates treatment-resistant depression. It can also predict the time to response with SSRI therapy.
Special Instructions
Prior Authorization is available but not required for this test. If the process is pursued, the necessary documentation should accompany the specimen. NY State clients must have informed consent documented and on file. For maternal cell contamination studies accompanying cord blood, maternal blood specimen is required for comprehensive analysis.
Limitations
Specimens from patients who have received recent blood transfusions or stem cell transplants may reflect incorrect genotype results due to donor DNA presence. Post-transplant results may not indicate the patient's original genotype. The test does not provide explicit dosing recommendations and should be used to support clinical decision-making. Certain genetic variants may not be detected due to insufficient DNA quality from saliva specimens, possibly necessitating additional specimens for robust results.
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
LOINC Codes
- 94753-1
- 94401-7
- 94402-5
- 94403-3
- 74511-7
- 72884-0
- 94254-0
- 72882-4
- 79720-9
- 104666-3
- 57132-3
- 79714-2
- 104667-1
- 46724-1
- 79716-7
- 104668-9
- 40425-1
- 79715-9
- 104669-7
- 94411-6
- 94412-4
- 94413-2
- 79712-6
- 57979-7
- 93190-7
- 93191-5
- 93192-3
- 94414-0
- 94415-7
- 94416-5
- 94417-3
- 94418-1
- 69047-9
- 48767-8
- 85069-3
- 62364-5
- 18771-6
- 81139-8
- 81145-5
- 81140-6
- 79717-5
Result Turnaround Time
3-14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
3 mL
Minimum Volume
Not provided
Container
Lavender top (EDTA)
Collection Instructions
Invert several times to mix blood. Send whole blood specimen in original tube. Do not aliquot. Whole blood collected postnatal from umbilical cord is acceptable.
Patient Preparation
A previous hematopoietic stem cell transplant from an allogenic donor will interfere with testing.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 4 days |
| Frozen | 4 days |