PT-Fibrinogen, Plasma
Use
This test is useful for detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin and differentiating hypofibrinogenemia from dysfibrinogenemia. Fibrinogen is a plasma protein synthesized in the liver, with the potential to transform into fibrin. It is involved in the clotting process and its abnormalities, whether inherited or acquired, can lead to significant clinical disorders. Congenital forms may manifest as afibrinogenemia or hypofibrinogenemia, while acquired deficiencies can arise due to various conditions such as disseminated intravascular coagulation and liver disease.
Special Instructions
This test is not orderable individually and is only available as part of a coagulation reflex profile. It is performed using the HemosIL PT-Fibrinogen kit on the Instrumentation Laboratory ACL TOP. The test requires plasma collected with sodium citrate as an anticoagulant. Specimens should be kept frozen to maintain stability during transport and storage.
Limitations
Results may be affected by excess heparin, hemoglobin, bilirubin, or degradation products in the plasma. Gross lipemia can cause underestimation of fibrinogen levels, and results should be interpreted with caution when such interference is suspected. It is important that specimens are collected and handled properly to ensure accurate results.
New York Approved
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 3255-7
- 3255-7
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Plasma Na Cit
Storage Instructions
Keep frozen
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |