Use

This test is useful for detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin and differentiating hypofibrinogenemia from dysfibrinogenemia. Fibrinogen is a plasma protein synthesized in the liver, with the potential to transform into fibrin. It is involved in the clotting process and its abnormalities, whether inherited or acquired, can lead to significant clinical disorders. Congenital forms may manifest as afibrinogenemia or hypofibrinogenemia, while acquired deficiencies can arise due to various conditions such as disseminated intravascular coagulation and liver disease.