Purines and Pyrimidines Panel, Random, Urine

Casandra

Casandra Test Code MC42980Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID PUPYUCPT Code 82542

Purines and Pyrimidines Panel, Random, Urine

Clinical Use

Use

Useful for evaluating patients with symptoms suspicious for disorders of purine and pyrimidine metabolism, monitoring patients with disorders of purine and pyrimidine metabolism, and laboratory evaluation of primary and secondary hyperuricemias. It aids in screening inherited disorders of purine and pyrimidine metabolism, of which at least 35 are known, presenting across neurological, immunological, hematological, and renal manifestations. The test profiles abnormal urinary levels of purines and pyrimidines quantitatively by LC‑MS/MS.

Special Instructions

Ordering guidance indicates this is the recommended screening test for suspected purine and pyrimidine metabolism disorders when clinical features are nonspecific; for conditions suggestive of molybdenum cofactor deficiency, isolated sulfite oxidase deficiency, or hereditary xanthinuria, SSCTU / S‑Sulfocysteine Panel, Urine should be ordered instead (SSCTU will be canceled if ordered alongside this test). Patient’s age is required. If not ordering electronically, use the Biochemical Genetics Test Request (T798).

Limitations

This test was developed and its performance characteristics determined by Mayo Clinic under CLIA standards, and has not been cleared or approved by the US FDA (i.e., it is not FDA‑approved).

Test Details

New York Approved