Q Fever Antibody Screen with Titer Reflex, Serum
Use
The Q Fever Antibody Screen with Titer Reflex, Serum is used for screening exposure to the bacterium Coxiella burnetii, which is the causative agent of Q fever. The test determines serological response to both phase I and phase II antigens of C. burnetii, which are indicative of acute or chronic infection. This assay is typically used for diagnostic purposes in individuals who are suspected to have Q fever and should not be used as a general population screening tool.
Special Instructions
If the initial serology result for Q fever is reactive, confirmation by indirect immunofluorescence assay will be performed at an additional charge. This reflex procedure helps confirm the presence of antibodies specific to Q fever's phase I and phase II antigens.
Limitations
The test results might show cross-reactivity with antibodies to other closely related intracellular organisms such as Rickettsia species. Serologic responses can vary depending on the timing of the specimen collection; hence specimens collected too early might not show detectable antibody levels. It is recommended to collect a second specimen 2 to 3 weeks later if clinical suspicion remains high.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 23019-3
- 23019-3
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
0.5 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, gross icterus, heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 7 days |