Rabbit Meat, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to rabbit meat by detecting IgE antibodies. It helps define the allergen responsible for eliciting signs and symptoms and can identify allergens responsible for allergic responses and/or anaphylactic episodes. Additionally, it validates sensitization before starting immunotherapy and investigates the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It is not useful in patients previously treated with immunotherapy to assess residual sensitivity or in cases where management does not rely on allergen identification.
Special Instructions
For optimal specimen collection, serum should be collected using a serum gel or red top tube, then centrifuged and aliquoted into a plastic vial. The preferred specimen volume is 0.5 mL for every 5 allergens. A minimum of 0.3 mL is required for one allergen, with more volume needed for additional allergens. Those conditions that cause improper specimen collection, inappropriate test selection, or interfering substances need to be avoided, as these could lead to diagnostic confusion.
Limitations
Test results must be interpreted in clinical context, as some individuals with clinically insignificant allergen sensitivity may have measurable IgE antibody levels in serum. False-positive results may occur in patients with markedly elevated serum IgE due to nonspecific binding. Test for IgE antibodies should not be used to determine if residual clinical sensitivity exists post-immunotherapy or in cases where medical management does not depend on allergen specificity.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 7642-2
- 7642-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens
Minimum Volume
0.3 mL
Container
Serum gel, Red top, Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
