Rat Urine Protein, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to rat urine protein and defining the allergen responsible for eliciting signs and symptoms. It helps identify allergens responsible for allergic response or anaphylactic episode. The test can confirm sensitization before starting immunotherapy and investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or when medical management does not depend on allergen specificity identification.
Special Instructions
Centrifuge and aliquot serum into a plastic vial for submission. Use the Serum gel container as preferred and the red top tube as acceptable for collection. Include the Allergen Test Request form if not ordering electronically.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in their serum. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE due to nonspecific binding to allergen solid phases. The test results must always be interpreted in the clinical context for accurate diagnosis and management of allergic diseases.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6226-5
- 6226-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens
Minimum Volume
0.3 mL for 1 allergen
Container
Serum gel or Red top (Submission: Plastic vial)
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
None specified
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
