Respiratory Profile, Region 8, Central Midwest (IA, IL, MO), Serum
Use
This test is useful for assessing sensitization to various inhalant allergens commonly found in the Central Midwest region, including Iowa, Illinois, and Missouri. It aids in defining the allergen responsible for eliciting signs and symptoms and identifying allergens responsible for allergic responses or anaphylactic episodes. It is used to confirm sensitization prior to beginning immunotherapy and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, it is not useful for patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or if the medical management does not depend upon identification of allergen specificity.
Special Instructions
For a listing of allergens available for testing, see the document 'Allergens - Immunoglobulin E (IgE) Antibodies'. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen. Complete specimen preparation by centrifuging and aliquoting serum into a plastic vial.
Limitations
Elevated concentrations of total IgE are not diagnostic for allergic disease and must be interpreted in the context of the patient, including age, sex, travel history, potential allergen exposure, and family history. A normal concentration of total IgE does not eliminate the possibility of allergic disease. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 48831-2
- 6020-2
- 6278-6
- 6025-1
- 6041-8
- 7155-5
- 6833-8
- 6178-8
- 53760-5
- 6078-0
- 6090-5
- 6095-4
- 6098-8
- 6096-2
- 6109-3
- 6263-8
- 19113-0
- 6232-3
- 6281-0
- 6189-5
- 6212-5
- 6233-1
- 6234-9
- 6085-5
- 6265-3
- 6274-5
- 6208-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1.55 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
