Rye, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to rye, defining the allergen responsible for eliciting signs and symptoms, and identifying allergens responsible for allergic response and/or anaphylactic episodes. It also helps confirm sensitization prior to beginning immunotherapy or investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. Testing for IgE antibodies is not particularly useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon identification of allergen specificity.
Special Instructions
For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies. If not ordering electronically, complete, print, and send an Allergen Test Request with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and test results must be interpreted in the clinical context. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. IgE levels may not be indicative of the clinical manifestation of the allergy, and the test should be considered as part of a complete allergy diagnostic workup.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 7674-5
- 7674-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Specimens with gross hemolysis or lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |