Use

Sezary Monitoring Flow Cytometry test is used to monitor the response to therapy in patients with previously diagnosed Sezary syndrome or mycosis fungoides. These are distinct but related T-cell lymphoproliferative disorders involving the skin and are commonly referred to as cutaneous T-cell lymphomas. Monitoring involves quantitative assessment of circulating neoplastic CD4-positive T-cells in peripheral blood, which is essential for disease staging and evaluating therapy response in CTCL. Flow cytometry remains the method of choice for estimating Sezary cells in peripheral blood, offering a more reproducible and timely alternative to morphological quantitation.