Smoothelin Immunostain, Technical Component Only
Use
This test is useful for distinguishing muscularis mucosae from muscularis propria. Smoothelin is a smooth muscle-specific marker expressed only in terminally differentiated smooth muscle cells as part of the cytoskeleton. It is expressed normally in the smooth muscle of the muscularis of the bowel as well as in smooth muscle in other organs.
Special Instructions
Not provided.
Limitations
Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. Best practice is for paraffin sections to be cut within 6 weeks. The charge of glass slides can be affected by environmental factors and subsequently may alter slide staining.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Smoothelin
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides.