Sole, IgE, Serum
Use
Establishing the diagnosis of an allergy to sole by defining the allergen responsible for eliciting signs and symptoms. It helps identify allergens responsible for an allergic response or anaphylactic episode and confirms sensitization prior to beginning immunotherapy. It is used to investigate allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in cases where medical management does not rely on allergen specificity identification.
Special Instructions
For a listing of available allergens for testing, see the Allergens - Immunoglobulin E (IgE) Antibodies document. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, necessitating test interpretation within the clinical context. False positives for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. The test is not useful for determining residual clinical sensitivity after immunotherapy or in cases where management does not depend on allergen specificity.
New York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 7709-9
- 7709-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |