Stemphyllium, IgE, Serum
Use
This test is useful for establishing a diagnosis of an allergy to Stemphyllium. It helps in defining the allergen responsible for eliciting signs and symptoms and identifying allergens responsible for allergic responses and/or anaphylactic episodes. It also confirms sensitization prior to starting immunotherapy and investigates the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in cases where medical management is independent of allergen specificity.
Special Instructions
The test should not be used to evaluate residual clinical sensitivity in patients treated with immunotherapy. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Some individuals may have measurable IgE antibodies despite clinically insignificant sensitivity to allergens. Results must be interpreted in clinical context. False positives may occur in patients with elevated serum IgE due to nonspecific binding to allergen solid phases.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6252-1
- 6252-1
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen; (0.05 mL x number of allergens) + 0.25 mL deadspace for more than 1 allergen
Container
Preferred: Serum gel. Acceptable: Red top. Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis and gross lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |