Strongyloides Antibody, IgG, Serum
Use
Screening for the presence of IgG-class antibodies to Strongyloides. This test detects IgG-class antibodies only and is used to suggest current or past infection. Strongyloidiasis is a parasitic infection caused by Strongyloides stercoralis, particularly prevalent in tropical and subtropical regions. Symptoms can include epigastric pain, diarrhea, nausea, vomiting, and respiratory issues. In immunocompromised patients, the infection may lead to hyperinfection and potentially fatal disseminated disease.
Special Instructions
This test is not useful for monitoring patient response to therapy as IgG-class antibodies to Strongyloides may remain detectable following resolution of infection. Proper specimen collection and handling are crucial as improper handling can lead to diagnostic confusion.
Limitations
False-positive results may occur due to other helminth infections. The assay should not be used solely for diagnosis; results must be correlated with other laboratory findings. False-negative results may occur during acute or localized infection. The absence of eosinophilia cannot be used to rule out infection. The seroprevalence of IgG-class antibodies to Strongyloides stercoralis ranges from 0% to 6.1% in the United States.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 34376-4
- 80660-4
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, Gross lipemia, Gross icterus, Heat inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 30 days |
| Frozen | 30 days |