Use

This test is useful for determining the minimal inhibitory concentrations (MIC) of Mycobacterium tuberculosis complex against second-line antimicrobial agents. It is commonly applied when the organism is resistant to first-line drugs such as rifampin and isoniazid, or when the physician intends to include a fluoroquinolone in the therapy. Testing includes agents such as amikacin, ethionamide, kanamycin, moxifloxacin, ofloxacin, p-aminosalicylic acid, rifabutin, and streptomycin. Results guide clinical decisions for patients with drug-resistant tuberculosis.