Use

This test aids in confirming the presence of synthetic glucocorticoids in serum specimens, especially in the context of suspected glucocorticoid exposure or when evaluating the cause of glucocorticoid-induced adrenal insufficiency. These synthetic glucocorticoids are extensively used as anti-inflammatory and immunosuppressive agents, and the test is crucial in detecting synthetic glucocorticoids that might not be documented in medical records, such as those used in non-prescription preparations. The test can also assess exposure leading to Cushing syndrome features or adrenal insufficiency through HPA axis suppression.