Thallium, Blood
Use
Detecting toxic exposure using whole blood specimens. Thallium is odorless, tasteless and found in trace amounts in the earth's crust. It is used in the manufacturing of electronic devices, switches, and closures, and had previously been used in rodenticides. The greatest exposure can occur from eating food, like fruits and vegetables, as it is easily taken up by plants. Accidental ingestion may lead to vomiting, diarrhea, leg pains, and later severe and sometimes fatal sensorimotor polyneuropathy. Peripheral neuropathy may occur within a week of exposure, while hair loss begins and continues for several weeks. Additional symptoms of acute ingestion include gastrointestinal pain, diarrhea, constipation, myalgias, chest pain, insomnia, optic neuritis, hypertension, cardiac abnormalities, Mees lines, and liver injury.
Special Instructions
This specimen container cannot be opened or used for any other testing before shipping. High concentrations of gadolinium and iodine may interfere with most ICP-MS metal tests. If gadolinium- or iodine-containing media has been administered, a specimen should not be collected for 96 hours.
Limitations
There are no significant cautionary statements; however, improper specimen collection and handling can affect results. The test has not been cleared or approved by the US Food and Drug Administration but is consistent with CLIA requirements.
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
LOINC Codes
- 5743-0
- 5743-0
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.3 mL
Container
Royal blue-top BD Vacutainer with EDTA blood collection tube (3 mL)
Collection Instructions
Send specimen in original tube. Do not aliquot. See Metals Analysis Specimen Collection and Transport for complete instructions.
Patient Preparation
If gadolinium or iodine-containing contrast media has been administered, avoid specimen collection for 96 hours.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |
