Tin, Serum
Use
The Tin, Serum test is used to measure the concentration of tin in the blood. Monitoring the levels of tin in serum can be particularly useful in cases where exposure to tin is suspected, such as in industrial settings or in environments where tin-based compounds are used. Elevated serum tin levels can indicate recent exposure to tin, and monitoring these levels can help in assessing the risk of toxicity or of cumulative exposure effects, guiding the management and intervention strategies for individuals at risk.
Special Instructions
Whole blood is the preferred specimen for monitoring exposure to tin, though this test specifically evaluates serum and plasma samples. It is crucial that blood is drawn in metal-free tubes to prevent contamination, and gel tubes are not permissible. Proper refrigeration and prompt processing are essential to maintain specimen integrity.
Limitations
This test does not establish a toxic range for tin in serum, as the toxicological profile for tin is not well-defined in this matrix. The test measures tin but does not assess clinical effects or predict toxicity levels directly. There's a possibility of contamination if guidelines for metal-free collection are not strictly followed. Mild hemolysis is acceptable, but gross hemolysis will lead to specimen rejection, potentially requiring redrawing and delaying diagnosis.
Methodology
Mass Spectrometry (ICP-MS)
Biomarkers
LOINC Codes
- 5748-9
- 5748-9
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.25 mL
Container
Plastic vial, metal-free
Collection Instructions
Draw blood in a metal free tube(s); serum gel tube is not acceptable. Spin down and send serum refrigerated.
Storage Instructions
Refrigerated (preferred): 14 days; Ambient: 72 hours; Frozen: 180 days
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 180 days |
