Toxocara Antibody, IgG, Serum

Casandra

Casandra Test Code MC85838Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID TOXCGCPT Code 86682

Toxocara Antibody, IgG, Serum

Clinical Use

Use

Toxocariasis is a zoonotic parasitic disease caused by the nematode, Toxocara, which primarily affects dogs and cats but can lead to infection in humans through ingestion of contaminated material containing Toxocara eggs. Diagnosis relies on antibody detection, as humans do not excrete eggs. This test aids in the diagnosis of Toxocara infection by detecting IgG antibodies to Toxocara species, helping to identify past or present infection. It is particularly relevant for individuals at higher risk, such as children, adolescents, and dog owners.

Special Instructions

The test uses an enzyme-linked immunosorbent assay (ELISA) method. Ensure specimens are handled correctly by centrifuging and aliquoting serum into a plastic vial. Avoid rejection by ensuring no gross hemolysis, lipemia, or heat-inactivation. The test is available for NY State clients and requires completion of a Kidney Transplant Test Request form if not ordered electronically.

Limitations

A single negative result does not exclude infection, particularly in cases of low parasitic burden or ocular toxocariasis where antibody levels might be low. False-negative results can occur in immunosuppressed individuals. False-positive results may arise due to other helminth infections. This test cannot differentiate between current and past infections, as measurable titers do not indicate the stage of infection.

Test Details

FDA Approved