Tree Panel #4, Serum
Use
This test is useful for establishing a diagnosis of an allergy to trees included in panel #4. It helps in identifying allergens responsible for allergic responses or anaphylactic episodes. The test can confirm sensitization before beginning immunotherapy and investigate specificity of allergic reactions to various allergens. Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or where medical management does not depend on identification of allergen specificity.
Special Instructions
This test uses a pooled allergen reagent, and a single qualitative class result and concentration is reported. It's appropriate as a first-tier test for allergic disease. Only one result is generated for each panel. In cases of a positive test, follow-up testing is required to differentiate between individual allergens in the panel.
Limitations
Individual allergen responses cannot be identified with this panel. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. Additionally, some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies; thus, results must be interpreted in the clinical context.
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 30182-0
- 30182-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Serum gel or Red top, submission in Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK, Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |
