Troponin T, 5th Generation, Plasma
Use
This test is useful for aiding in the exclusion of the diagnosis of acute coronary syndrome with a single plasma specimen, aiding in the diagnosis of acute coronary syndrome, monitoring acute coronary syndromes, estimating prognosis, and possibly monitoring patients with nonischemic causes of cardiac injury. Elevated levels of Troponin T are associated with adverse events in patients with ischemic heart disease.
Special Instructions
For specimen collection, the patient should not take multivitamins or dietary supplements containing biotin (vitamin B7) for 12 hours before specimen collection. Use the Cardiovascular Test Request Form (T724) if not ordering electronically.
Limitations
Elevations of cardiac troponin T (cTnT) do not necessarily indicate the presence of an ischemic mechanism. Many other disease states can be associated with cTnT elevations via mechanisms different from those causing acute coronary syndromes, such as trauma, heart failure, pulmonary embolism, kidney failure, and myocarditis. Clinical context must be considered to distinguish ischemic causes from others.
New York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 67151-1
- 67151-1
Result Turnaround Time
0-1 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
Light-green top (lithium heparin gel) tube preferred; green top (lithium heparin) acceptable
Collection Instructions
Lithium heparin gel tubes should be centrifuged within 2 hours of collection. The plasma should be aliquoted into a plastic vial within 2 hours of collection.
Patient Preparation
For 12 hours before specimen collection, avoid multivitamins or dietary supplements containing biotin (vitamin B7).
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 24 hours |
| Frozen | 365 days |